Publications

RESEARCH ARTICLES

  1. Ashhurst, A; McDonald, D.; Hanna, C.; Stanojevic, V.; Britton, W. J.; Payne R. J. Mucosal Vaccination with a Self-adjuvanted Lipopetide is Immunogenic and Protective against Mycobacterium Tuberculosis. J. Med. Chem. 2019, doi:10.1021/acs.jmedchem.9b00832.
  2. Kulkarni, S.; Watson, E. E.; Premdjee, B.; Conde-Frieboes, K. W.; Payne, R. J. Diselenide-Selenoester Ligation for Chemical Protein Synthesis. Nat. Protoc. 2019, 14, 2229-2257.
  3. Watson, E. E.; Ripoll-Rozad, J.; Lee, A. C.; Wu, M. C, L.; Pasch, T.; Premdjee, B.; Franck, C.; Sayers, J.; Pinto, M. F.; Martins, P. M.; Jackson, S. P.; Pereira, P. J. B.;Payne, R. J. Rapid Assembly of a Library of Anticoagulant Sulfoproteins. Proc. Natl. Acad. Sci. U. S. A. 2019, 116 (28), 13873-13878.
  4. Stoye, A.; Juillard, A.; Tang, A. H.; Legac, J.; Gut, J.; White, K.; Charman, S. A.; Rosenthal, P. J.; Grau, G. E. R.; Hunt, N. H.; Payne, R. J. Falcipain Inhibitors Based on the Natural product Gallinamide A are Potent in vitro and in vivo Antimalarials. J. Med. Chem. 2019, 62 (11), 5562-5578.
  5. Wei, R; Liu, H, Tang, A. H.; Payne, R. J.; Li, X. A Solution to Chemical Pseudaminylation via a Bimodal Glycosyl Donor for Highly Stereocontrolled α- and β-Glycosylation. Org. Lett. 2019, 21 (10), 3584-3588.
  6. Stanley, C. P.; Maghzal, G. J.; Shengule, S.; Giltrap, A. M.; Ayer, A.; Talib, J.; Chadha, P.; Prysyazhna, O.; Dunn, L. L.; Prado, F. M.; Stasch, J-P.; Yamamoto, Y.; Di Mascio, P.; Eaton, P.; Payne, R. J.; Stocker, R. Singlet Molecular Oxygen Regulates Vascular Tone and Blood Pressure in Inflammation. Nature, 2019, 566 (7745), 548-552.
  7. Sanchez, J.; E Huma, Z.; Lane, J. R.; Liu, X.; Bridgford, J. L.; Payne, R. J.; Canals, M.; Stone, M. J. Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1. J. Biol. Chem. 2019, 294 (10), 3464-3475.
  8. Hastwell, A. H.; Corcilius, L.; Williams, J. T.; Gresshoff, P. M.; Payne, R. J.; Ferguson, B. J. Triarabinosylation is required for nodulation-suppressive CLE peptides to systemically inhibit nodulation in Pisum sativum. Plant Cell Environ. 2019, 42 (1), 188-197.
  9. Conibear, A.; Watson, E. E.; Payne, R. J. Becker, C. F. W. Native Chemical Ligation in Protein Synthesis and Semi-Synthesis. Chem. Soc. Rev. 2018, 47 (24), 9046-9068. (invited review for special issue on “Protein Engineering”).
  10. McDonald, D.; Hanna, C.; Ashhurst, A.; Corcilius, L.; Byrne, S.; Payne, R. J. Synthesis of a Self-adjuvanting MUC1 Vaccine via Diselenide-Selenoester Ligation-Deselenization. ACS Chem. Biol. 2018, 13 (12), 3279-3285.
  11. Sayers, J.; Karpati, P. M. T.; Mitchell, N. J.; Goldys, A. M.; Kwong, S. M.; Firth, N.; Chan, B.; Payne R. J. Construction of Challenging Proline-Proline Junctions via Diselenide-Selenoester Ligation Chemistry. J. Am. Chem. Soc. 2018, 140(41), 13327-13334.
  12. Payne, R. J.; Winssinger, N. Editoral overview: Synthetic biomolecules. Current Opinion in Chemical Biology. 2018, 46, A3-A4.
  13. Robinson, S. D.; Mueller, A.; Clayton, D.; Starobova, H.; Hamilton, B. R.; Payne, R. J.; Vetter, I.; King, G. F.; Undheim, E. A. B. A comprehensive portrait of the venom of the giant red bull ant, Myrmecia gulosa, reveals a hyperdiverse hymenopteran toxin gene family. Science Adv. 2018, 4(9), eaau4640.
  14. Corcilius, L. C.; Liu, D. Y.; Ochoa, J. L.; Linington, R. G.; Payne, R. J. Synthesis and evaluation of analogues of the glycinocin family of calcium-dependent antibiotics. Org. Biomol. Chem. 2018, 16 (29), 5310-5320.
  15. Chisholm, T. S.; Clayton, D.; Dowman, L. J.; Sayers, J.; Payne, R. J. Native Chemical Ligation-Photodesulfurization in Flow. J. Am. Chem. Soc. 2018, 140 (29), 9020-9024. (journal cover image)
  16. Giltrap, A. M.; Haeckl, F. P. J.; Kurita, K. L.; Linington, R. G.; Payne, R. J. Synthetic Studies Towards the Skyllamycins: Total Synthesis and Generation of Simplified Analogues. J. Org. Chem. 2018, 83 (13), 7250-7270.
  17. Craik, D. J.; Payne, R. J. Emerging peptide Science in Australia (editorial). J. Pept. Sci. 2018, DOI: 10.1002/pep2.24080. (see cover image).
  18. Watson, E. E.; Liu, X.; Thompson, R. E.; Ripoll-Rozada, J.; Wu, M.; Alwis, I.; Gori, A.; Loh, C-T.; Parker, B. L.; Otting, G.; Jackson, S.; Pereira, P. J. B.; Payne, R. J. Mosquito-Derived Anophelin Sulfoproteins are Potent Anti-thrombotics. ACS Cent. Sci. 20184 (4), 468-476.
  19. Kulkarni, S.; Sayers, J.; Premdjee, B.; Payne, R. J. Rapid and Efficient Protein Synthesis Through Expansion of the Native Chemical Ligation Concept. Nat. Rev. Chem. 2018, 2, 0122.
  20. Je, B. I.; Xu, F.; Wu, Q.; Liu, L.; Meeley, R.; Gallagher, J. P.; Corcilius, L.; Payne, R. J.; Bartlett, M. E.; Jackson, D. The CLAVATA receptor FASCIATED EAR2 responds to distinct CLE peptides by signalling through two downstream effectors. ELife, 2018, 7, e35673.
  21. Nguyen K.; Garcia, A.; Sani, M. A.; Diaz, D.; Dubey, V.; Clayton, D.; Dal Poggetto, G.; Cornelius, F.; Payne, R. J.; Separovic, F.; Khandelia, H.; Clarke, R. J. Interaction of N-terminal peptide analogues of the Na+,K+-ATPase with membranes. Biochim. Biophys. Acta, 2018, 1860 (6), 1282-1291.
  22. Payne, R. J. Preface: Bioactive Molecules Australasia. Tetrahedron, 2018, 74 (12), 1165-1166.
  23. Imin, N.; Patel, N.; Corcilius, L.; Payne, R. J.; Djordjevic, M. CLE peptide tri-arabinosylation and peptide domain sequence composition are essential for SUNN-dependent autoregulation of nodulation in Medicago truncatula. New Phytologist, 2018, 218 (1), 73-80.
  24. Hawkins, P. M. E.; Giltrap, A. M.; Nagalingam, G.; Britton, W. J.; Payne, R. J. Total synthesis of ecumicin. Org. Lett. 2018, 20 (4), 1019-1022.
  25. Sayers, J.; Payne, R. J.; Winssinger, N. Peptide Nucleic Acid-Templated Selenocytine-Selenoester Ligation Enables Rapid miRNA Detection. Chem. Sci. 2018, 9, 896-903.
  26. Corcilius, L.; Elias, N. T.; Ochoa, J. L.; Linington, R. G.; Payne, R. J. Total synthesis of glycinocins A-C. J. Org. Chem. 2017, 82 (23), 12778-12785.
  27. Patel, N.; Mohd-Radzman, N.; Corcilius, L.; Crossett, B.; Connolly, A.; Cordwell, S.; Ivanovici, A.; Taylor, K.; Williams, J.; Binos, S.; Mariani, M.; Payne, R. J.; Djordjevic, M. Diverse peptide hormones affecting root growth identified in the Medicago truncatula secreted peptidome. Mol. Cell. Prot., 2017, 17 (1), 160-174.
  28. Pang, S. S.; Wijeyewickrema, L. C.; Hor, L.; Tan, S.; Lameignere, E.; Conway, E. M.; Mohlin, F.; Blom, A.; Liu, X.; Payne, R. J.; Whisstock, J. C.; Pike, R. N. The Structural Basis of Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech. J. Immunol. 2017, 199 (11), 3883-3891.
  29. Parker, B. L.; Burchfield, J.; Clayton, D.; Payne, R. J.; Kiens, B.; Wojtaszewski, J.; Richter, E.; James, D. Multiplexed temporal quantification of the exercise-regulated plasma peptidome. Mol. Cell. Prot., 2017, 16 (12), 2055-2068.
  30. Giltrap, A.; Haeckl, J.; Kurita, K.; Linington, R. G.; Payne, R. J. Total Synthesis of Skyllamycins A-C. Chem. Eur. J. 2017, 23 (60), 15046-15049.
  31. McAuley, J. L.; Corcilius, L.; Tan, H. X.; Payne, R. J. McGuckin, M. A.; Brown, L. E. The cell surface mucin MUC1 limits the severity of influenza A virus infection. Mucosal Immunol. 2017, 10 (6), 1581-1593.
  32. Croft, K.D.; Zhang, D.; Jiang, R.; Ayer, A.; Shengule, S.; Payne, R.J.; Ward, N.C. and Stocker, R. Structural requirements of flavonoids to induce heme oxygenase-1. Free Radical Biology and Medicine, 2017, 113, 165-175.
  33. Corcilius, L.; Hastwell, A. H.; Zhang, M.; Williams, J.; Mackay, J. P.; Gresshoff, P. M.; Ferguson, B. J.; Payne, R. J. Arabinosylation Modulates the Growth-Regulating Activity of the Peptide Hormone CLE40a from Soybean. Cell Chem. Biol. 2017, 24 (11), 1347-1355.
  34. Araman, C.; Thompson, R. E.; Wang, S.; Hackl, S.; Payne, R. J.; Becker, C. F. W. Semisynthetic Prion Protein (PrP) variants carrying glycan mimics at position 181 and 197 do not form fibrils. Chem. Sci. 2017, 8(9), 6626-6632.
  35. Hayward, J.; Sanchez, J.; Perry, A.; Huang, C.; Valle, M. R.; Canals, M.; Payne, R. J.; Stone, M. J. Ticks from diverse genera encode chemokine-inhibitory evasin proteins. J. Biol. Chem. 2017292 (38), 15670-15680.
  36. Phillips A. J.; Taleski, D.; Koplinski, C. A.; Getschman, A. E.; Moussouras, N. A.; Richard, A. M.; Peterson, F. C.; Dwinell, M. B.; Volkman, B. F.; Payne, R. J.; Veldkamp, C. T. CCR7 Sulfotyrosine Enhances CCL21 Binding. Int. J .Mol. Sci. 2017, 18 (9), 1857.
  37. Mitchell, N. J.; Sayers, J.; Kulkarni, S. S.; Clayton, D.; Goldys, A. M.; Ripoll-Rozada, J.; Pereira, P. J. B.; Chan, B.; Radom, L.; Payne, R. J. Accelerated Protein Synthesis via One-Pot Ligation-Deselenization Chemistry. Chem2017, 2(5), 703–715.
  38. Wang, X.; Sanchez, J.; Stone, M. Payne, R. J. Sulfation of Human Cytomegalovirus Protein UL22A Enhances Binding to the Chemokine RANTES. Angew. Chem. Int. Ed. 2017, 56 (29), 8490-8494.
  39. Hanna, C. C.; Kulkarni, S. S.; Watson, E. E.; Premdjee, B.; Payne, R. J. Solid-Phase Synthesis of Peptide Selenoesters via a Side-Chain Anchoring Strategy. Chem. Commun. 2017, 53, 5424-5427.
  40. McAuley, J. L.; Corcilius, L.; Tan, H. X.; Payne, R. J.; McGuckin, M. A.; Brown, L. E. The cell surface mucin MUC1 limits the severity of influenza A virus infection. Mucosal Immunol. 2017, 10, 1581-1593.
  41. Quan, D.; Nagalingam, G.; Payne, R. J. Triccas, J. A. New Tuberculosis Drug Leads from Naturally Occuring Compounds. Int. J. Infect. Dis. 201756, 212-220.
  42. Thompson, R. E.; Liu, X.; Ripoll-Rozada, J.; Alonso-Garcia, N.; Parker, B. L.; Pereira, P. J. B.; Payne, R. J. Tyrosine sulfation modulated activity of tick-derived thrombin inhibitors. Nat. Chem. 2017, 9, 909-917.
  43. Wang, S.; Corcilius, L.; Sharp, P. P.; Payne, R. J. Synthesis of a GlcNAcylated arginine building block for the solid phase synthesis of death domain glycopeptide fragments. Bioorg. Med. Chem. 2017, 25(11), 2895-2900.
  44. Tran, A. T.; Watson, E. E.; Pujari, V.; Conroy, T.; Dowman, L. J.; Giltrap, A. M.; Pang, A.; Wong, W.; Linington, R. G.; Mahapatra, S.; Saunders, J.; Charman, S. A.; West, N. P.; Bugg, T. D. H.; Tod, J.; Dowson, C. G.; Roper, D. I.; Crick, D. C.; Britton, W. J.; Payne, R. J. Sansanmycin Natural Product Analogues as Potent and Selective Anti-Mycobacterials that Inhibit Lipid I Biosynthesis. Nat. Commun. 2017, 8, 14414.
  45. Wang, S.; Corcilius, L.; Sharp, P. P.; Rajkovic, A.; Ibba, M.; Parker, B. L.; Payne, R. J. Synthesis of rhamnosylated arginine glycopeptides and determination of the glycosidic linkage in bacterial elongation factor P. Chem. Sci. 2017, 8, 2296-2302.
  46. Mitchell, N. J.; Kulkarni, S.; Wang, S. Malins, L. R. Payne, R. J. One-Pot Ligation-Oxidative Deselenization at Selenocysteine and Selenocystine. Chem. Eur. J. 2017, 23, 946-952. (selected as a “hot paper”).
  47. Stoye, A.; Nagalingam, G.; Britton, W. J.; Payne, R. J. Synthesis of Norfijimycin A with activity against Mycobacterium tuberculosis. Aust. J. Chem. 2017, 70, 229-232. (invited submission for special issue on Australian Peptide Science).
  48. O’Connor, G. D.; Chan, B.; Sanelli, J. A.; Cergol, K.; Dryza, V.; Payne, R. J.; Bieske, E.; Radom, L.; Schmidt, T. W. Hydrogen-adduction to Open-Shell Graphene Fragments: Spectroscopy, Thermochemistry and Astrochemistry. Chem. Sci.2017, 8, 1186-1194.
  49. Isahak, N.; Gody, G.; Malins, L. R.; Mitchell, N. J. Payne, R. J.; Perrier, S. Single Addition of an Allyl Amine Monomer Enables Access to End-Functionalized RAFT Polymers for Native Chemical Ligation. Chem. Commun. 201652(88), 12952-12955.
  50. Giltrap, A. M.; Dowman, L. J.; Nagalingam, G.; Ochoa, J. L,; Linington, R. G.; Britton, W. J.; Payne RJ. Total Synthesis of Teixobactin. Org. Lett. 201618(11), 2788-2791.
  51. Isahak, N.; Sanchez, J.; Perrier, S.; Stone, M. J.; Payne, R. J. Synthesis of polymers and nanoparticles bearing polystyrene sulfonate brushes for chemokine binding. Org. Biomol. Chem. 201614(24), 5652-5658.
  52. Rogers, S.; Fey, D.; McCloy, R. A.; Parker, B. L.; Mitchell, N. J.; Payne, R. J.; Daly, R. J.; James, D. E.; Caldon, C. E.; Watkins, D. N.; Croucher, D. R.; Burgess, A. PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells. J. Cell Sci. 2016129(7), 1340-1354.
  53. Williams, J. T.; Corcilius, L.; Kiefel, M. J.; Payne, R. J. Total Synthesis of Native 5,7-Diacetylpseudaminic Acid from N-Acetylneuraminic Acid. J. Org. Chem. 201681(6), 2607-2611.
  54. Kiermaier, E.; Moussion, C.; Veldkamp, C. T.; Gerardy-Schahn, R.; de Vries, I.; Williams, L. G.; Chaffee, G. R.; Phillips, A. J.; Freiberger, F.; Imre, R.; Taleski, D.; Payne, R. J.; Braun, A.; Förster, R.; Mechtler, K.; Mühlenhoff, M.; Volkman, B. F.; Sixt, M. Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science, 2016, 351(6269), 186-190.
  55. Mitchell, N. J.; Malins, L. R.; Liu, X.; Thompson, R. E.; Chan, B.; Radom, L.; Payne, R. J. Rapid Additive-Free Selenocystine–Selenoester Peptide Ligation. J. Am. Chem. Soc. 2015, 137(44), 14011-14014.
  56. Bashiri, G.; Johnston, J. M.; Evans, G. L.; Bulloch, E. M.; Goldstone, D. C.; Jirgis, E. N.; Kleinboelting, S.; Castell, A.; Ramsay, R. J.; Manos-Turvey, A.; Payne, R. J.; Lott, J. S. Baker, E. N. Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex. Acta Crystallogr. D Biol. Crystallogr., 2015, 71(11), 2297-2308.
  57. Sayers, J.; Thompson, R. E.; Perry, K. J.; Malins, L. R.; Payne, R. J. Thiazolidine-Protected β-Thiol Asparagine: Applications in One-Pot Ligation-Desulfurization Chemistry. Org. Lett. 201517(19), 4902-4905.
  58. McDonald, D. M.; Byrne, S. N.; Payne, R. J.  Synthetic Self-Adjuvanting Glycopeptide Cancer Vaccines. Front. Chem., 2015. [DOI: 10.3389/fchem.2015.00060]
  59. Malins, L. R.; Mitchell, N. J.; McGowan, S.; Payne, R. J. Oxidative Deselenization of Selenocysteine: Applications for Programmed Ligation at Serine. Angew. Chem. Int. Ed. 201554(43), 12716-12721.
  60. Watson, G.; Gunzburg, M.; Ambaye, N.; Lucas, W.; Traore, D.; Kulkarni, K.; Cergol, K.; Payne, R. J.; Panjikar, S.; Pero, S.; Perlmutter, P.; Wilce, M.; Wilce, J. Cyclic peptides incorporating phosphotyrosine mimetics as potent and specific inhibitors of the Grb7 breast cancer target. J. Med. Chem. 201558(19), 7707-7718.
  61. Santhakumar, G.; Payne, R. J. Studies Toward the Total Synthesis and Stereochemical Assignment of Microspinosamide. Aust. J. Chem. 201568(12), 1885-1889. (special issue for SynthCon3).
  62. Stone, M. J.; Payne, R. J. Homogeneous Sulfopeptides and Sulfoproteins: Synthetic Approaches and Applications To Characterize the Effects of Tyrosine Sulfation on Biochemical Function. Acc. Chem. Res., 201548(8), 2251–2261.
  63. Reeks, T.; Jones, A.; Brust, A.; Sridharan, S.; Corcilius, L.; Wilkinson, B. L.; Thaysen-Andersen, M.; Payne, R. J.; Kini, R. M.; Daly, N. L.; Alewood, P. F. A bifunctional O-glycosylated natriuretic peptide, TcNP-a, from the venom of Tropidechis carinatus has a defined alpha helix. Angew. Chem. Int. Ed. 201554(16), 4828-4831.
  64. Malins, L. R.; Giltrap, A. M.; Dowman, L. J.; Payne, R. J. Synthesis of β-Thiol Phenylalanine for Applications in One-Pot Ligation–Desulfurization Chemistry. Org. Lett. 201517(9), 2070-2073.
  65. Malins, L. R.; Payne, R. J. Synthetic Amino Acids for Applications in Peptide Ligation-Desulfurization Chemistry. Aust. J. Chem. 201568(4), 521-537. (Invited submission for lead review article for the Sir John Cornforth Commemorative issue).
  66. Ludeman, J. P.; Nazari-Robati, M.; Wilkinson, B. L.; Huang, C.; Payne, R. J.; Stone, M. J. Phosphate modulates receptor sulfotyrosine recognition by the chemokine monocyte chemoattractant protein-1 (MCP-1/CCL2). Org. Biomol. Chem. 201513(7), 2162-2169.
  67. Manos-Turvey, A. Watson,E. E.; Sykes,M. L.; Jones,A. J. Baell, J. B. Kaiser,M.; Avery, V. M.;  Payne, R. J. Synthesis and Evaluation of Phenoxymethylbenzamide Analogues as Anti-Trypanosomal Agent. Med. Chem. Commun. 20156, 403-406. (Invited submission for special issue New Talent: Asia-Pacific).
  68. Conroy T.; Guo, J. T.; Elias, N.; Cergol, K. M.; Gut, J.; Legac, J.; Khatoon, L.; Liu, Y.; McGowan, S.; Rosenthal, P. J.; Hunt, N. H.; Payne, R. J. Synthesis of Gallinamide A Analogues as Potent Falcipain Inhibitors and Antimalarials. J. Med. Chem. 2014, 57(24), 10557-10563.
  69. Millard, C. J.; Ludeman, J. P.; Canals, M.; Bridgford, J. L.; Hinds, M. G.; Clayton, D. J.; Christopoulos, A.; Payne, R. J.; Stone, M. J. Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: the N-Terminal Region of CCR3 Bound to CCL11/Eotaxin-1. Structure, 2014, 22, 1571–1581. (highlighted in a preview article in Structure “Chemokine-Receptor Interactions: Solving the Puzzle, Piece by Piece).
  70. Malins, L. R.; Payne, R. J. Recent Extensions to Native Chemical Ligation for the Chemical Synthesis of Peptides and Proteins. Curr. Opin. Chem. Biol. 201422, 70-78.
  71. Santhakumar, G.; Payne, R. J. Total Synthesis of Polydiscamides B, C, and D via a Convergent Native Chemical Ligation-Oxidation Strategy. Org. Lett. 201416, 4500-4503.
  72. McDonald, D. M.; Wilkinson, B. L.; Corcillius, L.; Thaysen- Andersen, M.; Byrne, S. N.; Payne, R. J. Synthesis and Immunological Evaluation of Self-Adjuvanting MUC1-Macrophage Activating Lipopeptide 2 Conjugate Vaccine Candidates. Chem. Commun201450, 10273-10276.
  73. Liu, X.; Malins, L. R.; Roche, M.; Sterjovski, J.; Duncan, R.; Garcia, M. L.; Barnes, N. C.; Anderson, D. A.; Stone, M. J.; Gorry, P. R.; Payne, R. J. Site-Selective Solid-Phase Synthesis of a CCR5 Sulfopeptide Library to Interrogate HIV Binding and Entry. ACS Chem. Biol. 20149(9), 2074-2081.
  74. Thompson, R. E. Liu, X.;  Alonso-Garcia, N.; Pereira, P. J. B.; Jolliffe, K. A.; Payne, R. J. Trifluoroethanethiol: An Efficient Additive for One-Pot Ligation-Desulfurization Chemistry. J. Am. Chem. Soc. 2014136(23), 8161-8164.
  75. Huma, Z.; Ludeman, J. P.; Wilkinson, B. L.; Payne, R. J. Stone, M. J. NMR Characterization of Cooperativity: Fast Ligand Binding Coupled to Slow Protein Dimerization. Chem. Sci. 20145, 2783-2788.
  76. Hsieh, Y. S.; Wilkinson, B. L.; Wijeyewickrema, L. C.; Pike, R. N.; Payne, R. J. Total Synthesis of Homogeneous Variants of Hirudin P6: A Post-Translationally Modified Anti-Thrombotic Leech-Derived Protein. Angew. Chem. Int. Ed. 2014, 53, 3947-3951. (Highlighted in Chemistry in Australia).
  77. Thompson, R. E.; Collin, F.; Maxwell, A.; Jolliffe, K. A.; Payne, R. J. Synthesis of Full Length and Truncated Microcin B17 Analogues as DNA Gyrase Poisons. Org. Biomol. Chem. 201412(10), 1570-1578.
  78. Maghzal, G. J. Cergol, K. M.; Shengule, S. R.; Suarna, C.; Newington, D.; Kettle, A. J.; Payne, R. J.; Stocker, R. Assessment of Myeloperoxidase Activity by the Conversion of Hydroethidine to 2-Chloroethidium. J. Biol. Chem. 2014289(9), 5580-5595.
  79. Cergol, K. M.; Thompson, R. E.; Malins, L. R.; Turner, P.; Payne, R. J. One-pot peptide ligation-desulfurization at glutamate. Org Lett. 201416(1), 290-293.
  80. Malins, L. R.; Cergol, K. M. Payne, R. J. Chemoselective Sulfenylation and Peptide Ligation at Tryptophan. Chem. Sci. 20145, 260-266.
  81. Malins, L. R.; Mitchell, N. Payne, R. J. Peptide Ligation Chemistry at Selenol Amino Acids. J. Pept. Sci.201420(2), 64-77. (invited submission for a special issue on chemical protein synthesis).
  82. Corcilius, L.; Payne, R. J. Stereoselective Synthesis of Sialylated Tumor-Associated Glycosylamino Acids. Org. Lett. 201315(22), 5794-5797.
  83. Tran, A. T.; Wen, D.; West, N. P.; Baker, E. N.; Britton, W. J.; Payne, R. J. Inhibition Studies on Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU). Org. Biomol. Chem. 201311, 8113-8126.
  84. Thompson, R. E.; Chan, B.; Radom, L.; Jolliffe, K. A.; Payne, R. J. Chemoselective Ligation-Desulfurization at Aspartate. Angew. Chem. Int. Ed. 2013, 52(37), 9723-9727.
  85. Al Sheikha, D.; Wilkinson, B. L.; Santhakumar, G.; Thaysen-Andersen. M.; Payne, R. J. Synthesis of Homogeneous MUC1 Oligomers via a Bi-Directional Ligation Strategy. Org. Biomol. Chem. 2013, 11, 6090-6096.
  86. Ziarek, J. J.; Getschman, A. E.; Butler, S. J.; Taleski, D.; Stephens, B.; Kufareva, I.; Handel T.M.; Payne, R. J.; Volkman, B. F. Sulfopeptide Probes of the CXCR4/CXCL12 Interface Reveal Oligomer-Specific Contacts and Chemokine Allostery. ACS Chem. Biol. 2013, 8(9), 1955-1963.
  87. Giltrap, A. M.; Cergol, K. M.; Pang, A.; Britton, W. J.; Payne, R. J. Total synthesis of fellutamide B and deoxy-fellutamides B, C, and D. Mar. Drugs. 201311(7), 2382-2397.
  88. Collin, F.; Thompson, R. E.; Jolliffe, K. A.; Payne, R. J.; Maxwell, A. Fragments of the Bacterial Toxin Microcin B17 as Gyrase Poisons. PLoS ONE20138(4), e61459.
  89. Roche, M.; Salimi, H.; Duncan, R.; Wilkinson, B. L.; Chikere, K.; Moore, M. S.; Webb, N.; Zappi, N.; Sterjovski, J.; Flynn, J.; Ellett, A.; Gray, L. R.; Lee, B.; Jubb, B.; Westby, M.; Ramsland, P. A.; Lewin, S. R.; Payne, R. J.; Churchill, M. J.; Gorry, P. R. A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations. Retrovirology201310:43.
  90. Corcilius, L.; Santhakumar, G.; Stone, R. S.; Capiccioti, C. J.; Matthews, J. M.; Ben, R. N.; Payne, R. J. Synthesis of Peptides and Glycopeptides with Polyproline II Helical Topology as Potential Antifreeze Molecules. Bioorg. Med. Chem. 201321(12), 3569-3581. (invited submission for special issue for the 2012 Tetrahedron Prize for Bioorganic and Medicinal Chemistry, Professor Ashraf Brik).
  91. Tan, J. H. Y.; Ludeman, J. P.; Wedderburn, J.; Canals, M.; Hall, P.; Butler, S. J.; Taleski, D.; Christopoulos, A.; Hickey, M. J.; Payne, R. J.; Stone, M. J. Tyrosine Sulfation of Chemokine Receptor CCR2 Enhances Interactions with Both Monomeric and Dimeric Forms of the Chemokine Monocyte Chemoattractant Protein-1 (MCP-1). J. Biol. Chem2013288(14), 10024-10034.
  92. Malins, L. R.; Cergol, K. M.; Payne, R. J. Peptide Ligation-Desulfurization Chemistry at Arginine. ChemBioChem 20134(5), 559-563.
  93. Payne, R. J. Total Synthesis of Erythropoietin through the Development and Exploitation of Enabling Synthetic Technologies. Angew. Chem. Int. Ed. 201352(2), 505-507.
  94. Bakmiwewa, S. M.; Fatokun, A. A.; Tran, A.; Payne, R. J.; Hunt, N. H.; Ball, H. J. Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2. Bioorg. Med. Chem. Lett. 201222(24), 7641-7646.
  95. Wilkinson, B. L.; Day, S.; Chapman, R.; Perrier, S.; Apostolopoulos, V.; Payne, R. J. Synthesis and Immunological Evaluation of Self-Assembling and Self-Adjuvanting Tricomponent Glycopeptide Cancer-Vaccine Candidates. Chem. Eur. J. 201218(51), 16540-16548.
  96. Manos-Turvey, A; Cergol, K. M.; Salam, N. K.; Bulloch, E. M.; Chi, G.; Pang, A.; Britton, W. J.; West, N. P.; Baker, E. N.; Lott, J. S.; Payne, R. J. Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site. Org. Biomol. Chem. 201210(46), 9223-9236.
  97. Thompson, R. E.; Payne, R. J.; Jolliffe, K. A. Total Synthesis of Cyclocitropside A and Its Conversion to Cyclocitropsides B and C via Asparagine Deamination. Org. Lett.201214(19), 5110-5113.
  98. Andrews, D. U.; Heazlewood, B. R.; Maccarone, A. T.; Conroy, T.; Payne, R. J.; Jordan, M. J. Kable, S. H. Photo-tautomerization of Acetaldehyde to Vinyl Alcohol: A Potential Route to Tropospheric Acids. Science2012337, 1203-1206.
  99. Malins, L. R.; Payne, R. J. Synthesis and Utility of β-Selenol-Phenylalanine for Native Chemical Ligation-Deselenization Chemistry. Org Lett. 201214 (12), 3142-3145.
  100. Chi, G.; Manos-Turvey, A.; O’Connor, P. D.; Johnston, J. M.; Evans, G. L.; Baker, E. N.; Payne, R. J.; Lott, J. S.; Bulloch, E. M. Implications of Binding Mode and Active Site Flexibility for Inhibitor Potency against the Salicylate Synthase from Mycobacterium tuberculosis. Biochemistry. 201251 (24), 4868-4879.
  101. Duncan, R. C.; Mohlin, F.; Taleski, D.; Coetzer, T. H.; Huntington, J. A.; Payne, R. J.; Blom, A. M.; Pike, R. N.; Wijeyewickrema, L. C. Identification of a Catalytic Exosite for Complement Component C4 on the Serine Protease Domain of C1s. J. Immunol.2012189(5), 2365-2373.
  102. Hsieh, Y. S.; Wilkinson, B. L.; O’Connell, M. R.; Mackay, J. P.; Matthews, J. M.; Payne R. J. Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants. Org. Lett.201214(7), 1910-1913. (Highlighted in the Peptides virtual issue for research published in J. Am. Chem. Soc., Org. Lett. and J. Org. Chem).
  103. Tran, A. T.; West, N. P.; Britton, W. J.; Payne, R. J. Elucidation of Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors using a Fragment Elaboration Strategy. ChemMedChem20127(6), 1031-1043.
  104. Tan, J. H.; Canals, M.; Ludeman, J. P.; Wedderburn, J.; Boston, C.; Butler, S. J.; Carrick, A. M.; Parody, T. R.; Taleski, D.; Christopoulos, A.; Payne, R. J.; Stone, M. J. Design and receptor interactions of an obligate dimeric mutant of the chemokine monocyte chemoattractant protein-1 (MCP-1). J. Biol. Chem.2012287(18), 14692-14702.
  105. Wilkinson, B. L.; Stone, R. S.; Capiccioti, C. J.; Thaysen-Anderson, M.; Matthews, J. M.; Packer, N. H.; Ben, R. N.; Payne, R. J. Total Synthesis of Antifreeze Glycopeptides and Glycoproteins. Angew. Chem. Int. Ed.201251(15), 3606-3610.
  106. Graham, M. E.; Stone, R. S.; Robinson, P. E.; Payne, R. J. Synthesis and Protein Binding Studies of a Peptide Fragment of Clathrin Assembly Protein 180 AP180 Bearing an O-Linked β-N-Acetylglucosaminyl-6-Phosphate Modification. Org. Biomol. Chem. 201210, 2545-2551.
  107. Hsieh, Y. S.; Taleski, D.; Wilkinson, B. L.; Wijeyewickrema, L. C.; Adams, T. E.; Pike, R. N.; Payne, RJ. Effect of O-glycosylation and tyrosine sulfation of leech-derived peptides on binding and inhibitory activity against thrombin. Chem. Commun. 201248, 1547-1549. (Included in the 2012 Emerging Investigators Issue).
  108. Thaysen-Andersen, M.; Wilkinson, B. L.; Payne, R. J.; Packer, N. H. Site-specific characterisation of densely O-glycosylated mucin-type peptides using electron transfer dissociation ESI-MS/MS. Electrophoresis 201132(24), 3536-3545.
  109. Conroy, T.; Guo, J. T.; Linington, R. G.; Hunt, N. H.; Payne RJ. Total synthesis, stereochemical assignment, and antimalarial activity of gallinamide A. Chem. Eur. J. 201117(48), 13544-13552.
  110. Thomas, G. L.; Hsieh, Y. S.; Chun, C. K. Y.; Cai, Z. L.; Reimers, J. R.; Payne, R. J. Peptide ligations accelerated by N-terminal aspartate and glutamate residues. Org. Lett. 201113(18), 4770-4773.
  111. Taleski, D.; Butler, S. J.; Stone, M. J.; Payne, R. J. Divergent and Site-Selective Solid-Phase Synthesis of Sulfopeptides. Chem. Asian J. 20116(6), 1316-1320.
  112. Kakwere, H.; Payne, R. J.; Jolliffe, K. A. Perrier, S. Self-assembling macromolecular chimeras: Controlling fibrillization of a beta-sheet forming peptide by polymer conjugation. Soft Matter20117 (8), 3754-3757.
  113. West, N. P.; Cergol, K. M.; Xue, M.; Randall, E. J.; Britton, W. J.; Payne, R. J. Inhibitors of an essential mycobacterial cell wall lipase (Rv3802c) as tuberculosis drug leads. Chem. Commun. 201147(18), 5166-5168. (Included as cover picture.)
  114. Dias, M.V.; Snee, W. C.; Bromfield, K. M.; Payne, R. J.; Palaninathan, S. K.; Ciulli, A.; Howard, N. I.; Abell, C.; Sacchettini, J. C.; Blundell, T. L. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011436, 729-739.
  115. Wilkinson, B. L.; Day, S.; Malins, L. R.; Apostolopoulos, V.; Payne, R. J. Self-Adjuvanting Multicomponent Cancer Vaccine Candidates Combining Per-Glycosylated MUC1 Glycopeptides and the Toll-like Receptor 2 Agonist Pam3CysSer. Angew. Chem. Int. Ed. 2011, 50, 1635-1639.
  116. Thompson, R. E.; Jolliffe, K. A.; Payne, R. J. Total Synthesis of Microcin B17 via a Fragment Condensation Approach. Org. Lett. 201113(4), 680-683.
  117. Zhu, J. Z.; Millard, C. J.; Ludeman, J. P.; Simpson, L. S.; Clayton, D. J.; Payne, R. J.; Widlanski, T. S.; Stone, M. J. Tyrosine Sulfation Influences the Chemokine-Binding Selectivity of Peptides Derived from Chemokine Receptor CCR3. Biochemistry 201150(9), 1524-1534.
  118. Tran, A. T.; Cergol, K. M.; West, N. P.; Randall, E. J.; Britton, W. J.; Bokhari, S. A. I; Ibrahim, M.; Lapthorn, A. J; Payne, R. J. Synthesis and Evaluation of Potent Ene-yne Inhibitors of Type II Dehydroquinases as Tuberculosis Drug Leads. ChemMedChem 2011, 6(2), 262-265. (Invited submission for special issue on rare and neglected diseases).
  119. Chim, N.; Habel, J. E.; Johnston, J. M.; Krieger, I.; Miallau, L.; Sankaranarayanan, R.; Morse, R. P.; Bruning, J.; Swanson, S.; Kim, H.; Kim, C. Y.; Li, H.; Bulloch, E. M.; Payne, R. J.; Manos-Turvey A.; Hung, L. W.; Baker, E. N.; Lott, J. S.; James, M. N.; Terwilliger, T. C.; Eisenberg, D. S.; Sacchettini, J. C.; Goulding, C. W.  The TB Structural Genomics Consortium: A decade of progress. Tuberculosis 201191(2), 155-172.
  120. Wilkinson, B. L.; Chun, C. K. Y.; Payne, R. J. Synthesis of MUC1 glycopeptide thioesters and ligation via direct aminolysis. Pept. Sci. 2011, 96(2), 137-146. (Special Issue: The Eighth Australian Peptide Conference: Peptides – Tools, Targets and Therapeutics.)
  121. Wilkinson, B. L.; Malins, L. R.; Chun, C. K.; Payne R. J. Synthesis of MUC1-lipopeptide chimeras. Chem Commun. 201046(34), 6249-6251.
  122. Conroy, T.; Guo, J. T.; Hunt, N. H.; Payne, R. J. Total Synthesis and Antimalarial Activity of Symplostatin 4. Org. Lett. 201012(23), 5576-5579.
  123. Tran, A. T.; Cergol, K. M.; Britton, W. J.; Bokhari, S. A. I.; Ibrahim, M.; Lapthorn, A. J.; Payne, R. J. Rapid assembly of potent type II dehydroquinase inhibitors via “Click” chemistry. Med. Chem. Commun. 2010, 1, 271-275.
  124. Holt, D. J.; Payne, R.J.; Chow, W.Y. and Abell, C. Fluorosurfactants for microdroplets: interfacial tension analysis. J. Colloid Interface Sci. 2010350, 205-211.
  125. Manos-Turvey A.; Bulloch, E. M. M.; Rutledge, P. J.; Baker, E. N.; Lott, J. S.; Payne, R. J. Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI). ChemMedChem 20105, 1067-1079. (Included as cover picture).
  126. Conroy, T.; Jolliffe, K. A.; Payne, R. J. Synthesis of N-linked glycopeptides via solid-phase aspartylation. Org. Biomol. Chem. 20108, 3723-3733.
  127. Payne, R.J.; Bulloch, E. M. M.; Kerbarh, O.; Abell, C. Inhibition of chorismate-utilising enzymes by 2-amino-4-carboxypyridine and 4-carboxypyridone and 5-carboxypyridone analogues. Org. Biomol. Chem. 20108, 3534-3542.
  128. Kakwere, H.; Chun C. K. Y.; Jolliffe, K. A.; Payne, R. J.; Perrier S. Polymer-peptide chimeras for the multivalent display of immunogenic peptides. Chem. Commun. 201046, 2188-2190. (Included as cover picture).
  129. Holt, D. J.; Payne, R. J.; Abell, C. Synthesis of novel fluorous surfactants for microdroplet stabilisation in fluorous oil streams. J. Fluor. Chem. 2010131, 398-407.
  130. Payne, R. J.; Wong, C-H. Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins. Chem. Commun. 201046, 21-43.
  131. Garner, J.; Jolliffe, K. A.; Harding, M. M.; Payne, R. J. Synthesis of homogeneous antifreeze glycopeptides via a ligation-desulfurisation strategy. Chem. Commun. 2009, 6925-6927.
  132. Thomas, G. L.; Payne, R. J. Phosphate-assisted ligation. Chem. Commun. 2009, 4260-4262. (Highlighted in meet our authors section).
  133. Chun, C. K. Y.; Payne, R. J. Synthesis of MUC1 peptide and glycopeptide dendrimers. Aust. J. Chem. 2009, 1339-1343 (Invited submission for feature edition on Bioconjugate Chemistry).
  134. Conroy, T.; Jolliffe, K. A.; Payne, R. J. Efficient use of the Dmab protecting group: applications for the solid-phase synthesis of N-linked glycopeptides. Org. Biomol. Chem. 20097, 2255-2258.
  135. Payne, R. J.; Bulloch, E. M. M.; Toscano, M. M.; Jones, M. A.; Kerbarh, O.; Abell, C. Synthesis and evaluation of 2,5-dihydrochorismate analogues as inhibitors of the chorismate-utilising enzymes. Org. Biomol. Chem. 20097, 2421-2429.
  136. Bennett, C. S.; Dean S. M.; Payne R.J.; Ficht S.; Brik A.; Wong C.-H. Sugar-Assisted Glycopeptide Ligation with Complex Oligosaccharides: Scope and Limitations. J. Am. Chem. Soc. 2008130, 11945-11952.
  137. Payne, R. J.; Ficht, S.; Greenberg, W. A.; Wong, C.-H. Cysteine-Free Peptide and Glycopeptide Ligation by Direct Aminolysis. Angew. Chem. Int. Ed. Engl. 200847, 4411-4415.
  138. Ficht, S.; Payne, R. J.; Guy, R. T.; Wong, C.-H. Solid-Phase Synthesis of Peptide and Glycopeptide Thioesters through Side-Chain-Anchoring Strategies. Chem. Eur. J. 200814, 3620-3629.
  139. Payne, R. J.; Ficht, S.; Tang, S.; Brik, A.; Yang, Y-Y.; Case D.; Wong C.-H. Extended Sugar-Assisted Glycopeptide Ligations: Development, Scope and Applications. J. Am. Chem. Soc. 200744, 13527-13536.
  140. Ficht, S.; Payne, R. J.; Brik, A.; Wong, C.-H. Second-Generation Sugar-Assisted Ligation: A Method for the Synthesis of Cysteine-Containing Glycopeptides. Angew. Chem. Int. Ed. Engl. 200746, 5975-5979.
  141. Payne, R. J.; Peyrot, F.; Kerbarh, O.; Abell, A. D.; Abell, C. Rational Design, Synthesis, and Evaluation of Nanomolar Type II Dehydroquinase Inhibitors. ChemMedChem 20072(7), 1015-1029.
  142. Payne, R. J.; Riboldi-Tunnicliffe, A.; Kerbarh, O.; Abell, A. D.; Lapthorn, A. J.; Abell, C. Design, Synthesis, and Structural Studies on Potent Biaryl Inhibitors of Type II Dehydroquinases. ChemMedChem 20072(7), 1010-1013.
  143. Abell, A. D.; Jones, M. A.; Neffe, A. T.; Aitken, S. G.; Cain, T. P.; Payne, R. J.; McNabb, S. B.; Coxon, J. M.; Stuart, B. G.; Pearson, D.; Lee, H. Y.-Y.; Morton, J. D. Investigation into the P3 Binding Domain of m-Calpain Using Photoswitchable Diazo- and Triazene-dipeptide Aldehydes: New Anticataract Agents. J. Med. Chem. 200750(12), 2916-2920.
  144. Toscano, M. D.; Payne, R. J.; Chiba, A.; Kerbarh, O.; Abell, C.  Nanomolar inhibition of type II dehydroquinase based on the enolate reaction mechanism. ChemMedChem 2007,  2(1), 101-112.
  145. Payne, R. J.; Bulloch, E. M. M.; Abell, A. D.; Abell, C.  Design and synthesis of aromatic inhibitors of anthranilate synthase. Org. Biomol. Chem.  20053(20), 3629-3635.
  146. Payne, R. J.; Toscano, M. D.; Bulloch, E. M. M.; Abell, A. D.; Abell, C. Design and synthesis of aromatic inhibitors of anthranilate synthase. Org. Biomol. Chem. 20053(12), 2271-2281. (Included as a cover picture)
  147. Payne, R. J.; Kerbarh, O.; Miguel, R. N.; Abell, A. D.; Abell, C. Inhibition studies on salicylate synthase. Org. Biomol. Chem. 20053(10), 1825-1827.
  148. Payne, R.; Edmonds, M.  Isolation of shikimic acid from star aniseed. J. Chem. Ed.  200582(4), 599-600. (Included as a cover picture)
  149. Kerbarh, O.; Bulloch, E. M. M.; Payne, R. J.; Sahr, T.; Rebeille, F.; Abell, C.; Mechanistic and Inhibition Studies of Chorismate-Utilising Enzymes. Biochem. Soc. Trans. 200533(4), 763-766.
  150. Payne, R. J.; Daines, A. M.; Clark, B. M.; Abell, A. D.  Synthesis and protein conjugation studies of vitamin K analogues. Bioorg. Med. Chem. 200412(22), 5785-5791.
  151. Payne, R. J.; Brown, K. M.; Coxon, J. M.; Morton, J. D.; Lee, H. Y.-Y.; Abell, A. D. Peptidic Aldehydes Based on α – and β -Amino Acids: Synthesis, Inhibition of m-Calpain, and Anti-Cataract Properties. Aust. J. Chem. 200457(9), 877-884.
  152. Daines, A. M.; Payne, R. J.; Humphries, M. E.; Abell, A. D.  The synthesis of naturally occurring vitamin K and vitamin K analogues. Curr. Org. Chem.  20037(16), 1625-1634.
  153. de Zwart, F. J.; Slow, S.; Payne, R. J.; Lever, M.; George, P. M.; Gerrard, J. A.; Chambers, S. T. Glycine Betaine and Glycine Betaine Analogues in Common Foods. Food Chem. 200383(2), 197-204.
  154. Payne, R. J.; Abell, A. D. Protein binding studies of vitamin K analogues for use in an immunological assay.  Chem. New Zealand2002,  66(1), 16-26.
  155. Lundy, S. D.; Payne, R. J.; Giles, K. R.; Garrill, A. Heavy metals have different effects on mycelial morphology of Achlya bisexualis as determined by fractal geometry.  FEMS Microbiol. Lett.  2001201(2), 259-263.

BOOK CHAPTERS, HIGHLIGHTS & FORWARDS

  1. Payne, R. J.; Winssinger, N. Editorial Overview: Synthetic biomolecules. Current Opinion in Chemical Biology 2018, 46, A3-A4.
  2. Payne, R. J. Preface: Bioactive Molecules Australiasia. Tetrahedron 2018, 74(12), 1165-1166.
  3. Premdjee, B.; Payne, R. J. Synthesis of Proteins by Native Chemical Ligation–Desulfurization Strategies. in Chemical Ligation: Tools for Biomolecule Synthesis and Modification (Wiley), 2017, 161-222.
  4. Watson, E. E.; Payne, R. J. 4-Nitrophenylchloroformate. Encyclopedia for Reagents in Organic Synthesis 2017.
  5. Malins, L. R.; Payne, R. J. Modern Extensions of Native Chemical Ligation for Chemical Protein Synthesis. Top. Curr. Chem. (Springer), 2014, DOI: 10.1007/128_2014_584 (invited book chapter).
  6. Payne, R. J. Carbohydrates: The Essential Molecules of Life. Aust. J. Chem. 2009, 62, 1-2.
  7. Bennett, C. S.; Payne, R. J.; Koeller, K. M.; Wong, C.-H. Synthesis and applications of biologically relevant glycopeptides. Glycoscience (Vol III), 2008, Fraser-Reid, B.O.; Tatsuta, K.; Thiem, J.; Coté, G.L.; Flitsch, S.; Ito, Y.; Kondo, H.; Nishimura, S.; Yu, B. (Eds.) Springer Berlin Heidelberg, 1795-1857.

 

PATENTS

  1. Chisholm, T; Payne R. J. “Flow Peptide and Protein Synthesis” Australian Provisional Patent filed 06/06/2018.
  2. Tran, A. T.; Tran, W.; Britton, W. J.; Payne, R. J. “Novel TB Drugs” Australian Provisional Patent filed 17/12/2016.
  3. Pereira, P. J. B.; Jackson, S. J.; Payne, R. J. “Antithrombotic Peptides” Australian Provisional Patent filed 17/12/2016.
  4. Mitchell, N. J.; Malins, L. R.; Payne, R. J. “Protein Synthesis” Australian Provisional Patent filed 26/02/2015.
  5. Thompson, R. E.; Payne, R. J. “Peptide Ligation” Australian Provisional Patent filed 22/05/2014.
  6. Wilkinson, B. L.; Day, S.; Apostolopoulos, V; Payne, R. J. “Glycopeptide Cancer Vaccine Candidates” APPA Number: 2010905492, December 15, 2010.
  7. West, N.; Payne, R. J.: Britton, W. J. “Inhibitors of Rv3802c as Tuberculosis Drug Leads” APPA Number: 2011900133, January 14, 2011.
  8. Thomas, G. L.; Payne R. J. “Peptide Synthesis” 20090331 – 61631AUV00 – Filed Provisional Application.
  9. Brik, A.; Yang, Y.-Y.; Ficht, S; Payne, R. J.; Wong, C.-H. “Method of Preparing Glycopeptides” Application Serial Number-60/743,666, U.S. Patent Application filed March 22, 2007.